When playing as a survivor, players assume the role of Dwight Fairfield, Meg Thomas, Claudette Morel, Jake Park, Nea Karlsson, Laurie Strode, William 'Bill' Overbeck, Ace Visconti, Feng Min, or David King.[7][8] The goal of the survivors is to escape the enclosed area, which can be done in one of two ways: either by repairing a certain number of disabled generators (usually, the number of generators is one greater than the number of survivors playing) to provide power to switches which open large, metal doors leading out of the area; or by escaping through a hatch which only (barring the use of a key) opens when there is one survivor left and at least two generators have been successfully repaired. The hatch will appear at one of several predetermined locations.[9] The survivors' movement options consist of sprinting, walking, crouch-walking, or crawling. They must elude the killer by using the darkness, crouching behind objects, and hiding in buildings, foliage, or inside lockers.

The survivors have the option to utilize up to four perks per match that affect how they play each game. Each of the survivors has a set of three unique-to-them perks that are only available to that survivor until the ability to teach them to other survivors is unlocked. These perks can be unlocked and upgraded in the Bloodweb using bloodpoints and each blood web can only hold up to two perks. These perks can range from giving a burst of speed when running from the killer, to being able to self-heal without a first aid kit, to unlocking the ability to sabotage meat hooks without a toolbox. There are also a multitude of 'universal' perks that are available to unlock by any survivor.
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